PLLA (poly-L-lactic acid) is a biodegradable polymer. It is a polymer compound polymerized from L-lactic acid monomers. It has good biocompatibility and biodegradability and will eventually degrade into water and carbon dioxide. PLLA is commonly used in medical fields such as absorbable sutures and tissue engineering. Its mechanism for stimulating collagen production involves its biocompatibility and biodegradability. Because of this property of PLLA, PLLA was developed as a subdermal filler to stimulate collagen regeneration under the skin.
PLLA has the following properties:
Biocompatibility: The presence of PLLA in tissues will not cause significant foreign body reactions or inflammatory reactions because it is a biodegradable material and its breakdown products are relatively harmless to the body. This biocompatibility promotes normal growth and regeneration of surrounding tissue.
Biodegradability: PLLA can gradually degrade into lactic acid in the body and be metabolized and excreted by the body. This degradation releases lactic acid, which acts as a precursor to collagen biosynthesis and promotes collagen production.
Mechanical stimulation: The presence of PLLA material can provide a mechanical stimulation to promote the proliferation and repair of surrounding tissue, which may also contribute to the production of collagen.
Increased skin firmness: Stimulating collagen regeneration can increase skin elasticity and firmness, making skin appear younger.
Wrinkle reduction: Collagen is an important protein in the skin that maintains elasticity and smoothness. Stimulating collagen regeneration can reduce fine lines and wrinkles on the skin, making the skin surface smoother.
Improved skin texture: Due to the supportive role of collagen in the skin, its regeneration can improve skin texture, making the skin softer, smoother and more even-toned.
Improves skin's radiance: Stimulating collagen regeneration helps improve uneven skin tone and dullness, making skin look more radiant and healthy.
Long-lasting results: The collagen regeneration effects stimulated by PLLA are often longer-lasting than some other fillers because it activates the production and redistribution of autologous collagen.
Based on the characteristics of PLLA, Singderm injectable PLLA filler is new launched as the new solution for facial rejuvenation. Singderm injectable PLLA filler is a white lyophilized powder, requiring reconstitution with sterile water for injection to form a suspension. It can stimulates collagen regeneration for nasolabial areas. With the increase in age, skin cell vitality diminishes, collagen gradually decreases, and aging symptoms such as "depression," "looseness," and "sagging" appear on the skin. Singsumile injectable PLLA filler is for solve these skin problems. With PLLA in it, it can continuous stimulation for collagen regeneration. It is administered by injection into the deep layers of the dermis to achieve wrinkle-filling effects. The Injectable Plla Filler undergoes complete degradation within the human body.
Overall, PLLA promotes collagen production by promoting normal growth and regeneration of surrounding tissue through its biocompatibility, biodegradability and possible mechanical stimulation.
